The bug
The command block GUI button for toggling whether output is tracked uses X and O as text, which is also read by the narrator.
However, it is questionable how useful that actually is since X looking similar to a cross (for disabled) might not be obvious for a person with reduced vision.
How to reproduce
Enable the narrator in the accesibility options
Place a command block and right click it
Click on the button with the text
Ofor toggling output tracking
❌ The narrator reads "track output X button"
Affects 1.20.6 and 1.21 Pre-Release 3: